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氩离子凝固术及窄带成像技术结合质子泵抑制剂在Barrett食管诊治中的应用 被引量:1

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摘要 目的:研究氩离子凝固术及窄带成像技术结合质子泵抑制剂在治疗Barrett食管中的有效性、安全性。方法:使用内镜下窄带成像技术(NBI)结合病理检查诊断Barrett食管51例,其中35例按内镜下形态及大小接受氩离子凝固术(APC)结合质子泵抑制剂(PPI)治疗。术后1、3、6个月进行内镜及病理随访。结果:35例接受治疗的患者中再生的鳞状上皮间混有岛状的柱状上皮2例(5.7%),达到完全的鳞状上皮再生33例(94.3%);术后3个月随访反流症状全消失23例,明显缓解12例,无效0例;术后6个月随访有3例(8.6%)出现内镜下可见的复发。结论:内镜下NBI应用对诊断BE、区别不同程度异型增生及早期发现食管腺癌有临床意义;内镜下氩离子凝固术结合质子泵抑制剂及胃动力药物治疗BE操作简便、安全、并发症少,近期疗效显着。
出处 《交通医学》 2011年第4期373-374,377,共3页 Medical Journal of Communications
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参考文献6

  • 1Espinel J,Pinedo E,Rascarachi G.Endoscopic mucosal resec- tion with a muhiband ligator for the treatment of Barrett's high-grade dysplasia and early gastric cancer [J].Rev EspEnferm Dig,2009,101(6) :403-407.
  • 2Tytgat G. Editorial:gastroesophageal reflux disease Anno 2010-many unsolved questions and unmet needs [J].J Dig Dis,2010,11 (2):67-71.
  • 3房殿春,许同铭,赵晶京.Barrett食管诊治共识(草案,2005,重庆)[J].中华消化杂志,2006,26(2):138-139. 被引量:53
  • 4Hornick JL, Blount PL, Sanches CA,et al. Biologic properties of columnar epithelium enderneath reepithelialized squamous mucosa in Barrett's esophagus[J]. Am J Surg Pathol,2005,29 (3):372-380.
  • 5邹多武.抑酸对Barrett食管的治疗价值[J].中华消化杂志,2006,26(2):121-122. 被引量:23
  • 6Basu KK,Pick B,Bale R,et al.Efficacy and one year follow up of argon plama coagulation,therapy for ablation of Barrett's esophagus[J].Gut,2002,51 (6):776-780.

二级参考文献7

  • 1Shaheen NJ,Crosby MA,Bozymski EM,at al.Is there publication bias in the reporting of cancer risk in Barrett's esophagus?Gastroenterology,2000,119:333-338.
  • 2Menges M,Muller M,Zeitz M.Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis,and effect of proton pump inhibitor therapy.Am J Gastroenterol,2001,96:331-337.
  • 3Orlando RC.Mechanisms of epithelial injury and inflammation in gastrointestinal diseases.Rev Gastroenterol Disord,2002,2:S2-S8.
  • 4Souza RF,Shewmake K,Terada LS,et al.Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus.Gastroenterology,2002,122:299-307.
  • 5Buttar NS,Wang KK,Sebo TJ,et al.Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma.Gastroenterology,2001,120:1630-1639.
  • 6El-Serag HB,Aguirre TV,Davis S,et al.Proton pump inhibitors are associated with reduced incidence of dysplasia in Barrett's esophagus.Am J Gastroenterol,2004,99:1877-1883.
  • 7Carlson N,Lechago J,Richter J,et al.Acid suppression therapy may not alter malignant progression in Barrett's metaplasia showing p53 protein accumulation.Am J Gastroenterol,2002,97:1340-1345.

共引文献71

同被引文献7

  • 1戈之铮,陆秋云,薛寒冰,李伟光,戴军,李晓波,胡运彪.内镜窄带成像技术在诊断Barrett食管中的作用研究[J].中华消化内镜杂志,2007,24(1):14-18. 被引量:36
  • 2Canto MI. Diagnosis of Barrett esophagus and esoplasia:east meet west[ J]. Dig Endosc,2006,18 ( 1 ) :36-40.
  • 3Toyoda H, Rubio C, Befrits R, et ak Detection of intestinal meta-pla- sia in distal esophagus and esophagogastric junction by enhanced-mag- nification endoscopy[J]. Gastrointest Endosc ,2004,59( 1 ) :15-21.
  • 4Kim SL, Waring JP, Spechler SJ, et al. Diagnosis inconsistencies in Barrett' s esophagus. Department of Veterans Affairs Gastroesophageal Reflux Study Group [ J ]. Gastroenterology, 1994,107 (4) :945-949.
  • 5Kara MA, Ennahachi M, Fockens P, et al. Detection and classi-fica- tion of the mucosal and Vascular patterns ( mucosal morphology ) in Barrett' s esophagus by using narrow band imaging [ J ]. Gastrointest Endosc, 2006, 64(2) : 155-166.
  • 6Sharma P ,Bamsal A,Mathur S,et al. The utility of a novel narrow band imaging endoscopy system in patients with Barrett' s esophagus [ J ]. Gas- trointest Endosc,2006,64(2) :167-175.
  • 7Barrett食管诊治共识(2011修订版,重庆)[J].中华消化内镜杂志,2011,28(8):421-422. 被引量:60

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