酚妥拉明和阿拉明联合治疗小儿重症肺炎的临床疗效分析

The Clinical Analysis of Phentolamine Combined with Alamin for Severe Pneumonia in Children

目的探讨酚妥拉明和阿拉明联合治疗小儿重症肺炎的临床治疗效果。方法 76例小儿重症肺炎患儿根据入院先后顺序随机分为观察组和对照组各38例,两组患儿均给予常规抗炎、平喘、强心、利尿、吸氧等治疗措施。观察组在上述治疗的基础上应用酚妥拉明、阿拉明进行治疗。治疗期间进行血尿便常规、血生化、心电图检查,并比较两组患者的治疗效果。结果与对照组的总有效率71.1%比较,观察组的总有效率92.1%,明显高于对照组(P<0.05)。观察组治疗后的咳嗽、气促等临床症状的消失时间明显短于对照组,肺部啰音的消失时间明显短于对照组,差异有统计学意义(P<0.05);虽然观察组患儿住院时间短于对照组,但差异不显著(P>0.05)。结论酚妥拉明和阿拉明联合治疗小儿重症肺炎疗效优于常规基础用药,联合用药可以明显改善患儿的咳嗽、气促等临床症状以及使其肺部啰音明显减轻,且未见明显副作用,值得广泛推广和应用。

Objective To investigate the effect of phentolamine combined alamin for severe pnenmonia in children. Methods All 76 patients with severe pneumonia were divided into two groups, each 38 cases. Two groups children were given conventional antiinflammatory, asthma, cardiac, diuretic, oxygen and other therapeutic measures. Based on the application of phentolamine, observed group was treated with Alamin. During treatment for hematuria will be routine, blood biochemistry, ECG, and patient outcomeswere compared. Results Compared with the control group, the total effective of observation group （92.1%）was significantly higher （P 〈 0.05 ）. After treatment the clinical symptoms of cough, shortness of breath disappeared significantly shorter than the control group, signs of pulmonary rules disappeared significantly shorter than the control group （ P 〈 0.05 ）. Although the observation group of children and shorter hospital stay than the control group, but the difference was not significant （P 〉 0.05 ）. Conclusion Phentolamine and alamin in treatment of severe pneumonia in children can improve clinical effect. Combined therapy can significantly alleviate children＇s cough, shortness of breath and other symptoms, and to significantly reduce pulmonary rules, and no significant side effects, which should be widely promoted and applied.