期刊文献+

培美曲塞单药治疗晚期非小细胞肺癌的疗效观察 被引量:1

下载PDF
导出
摘要 目的评价培美曲塞单药治疗老年晚期肺癌的近期疗效和不良反应。方法 20例老年晚期非小细胞肺癌患者给予培美曲塞单药化疗,按WHO标准评价近期疗效及不良反应。结果 20例患者获得CR 0例,PR 4例,NC 5例,RR为20%,一年生存率为43%。主要不良反应为胃肠道反应、骨髓抑制、皮疹等。结论培美曲塞单药治疗老年晚期非小细胞肺癌有效率为20%,不良反应轻,患者可耐受。
作者 郑阜娟
出处 《中国医学创新》 CAS 2011年第30期131-132,共2页 Medical Innovation of China
  • 相关文献

参考文献3

二级参考文献47

  • 1[1]Fry W, Phillips, Menck H. Ten-year survey of lung cancer treatment and survival in hospitals in United States. Cancer,1999, 86:1867
  • 2[2]Socinski M. Chemotherapy for stage Ⅳ non-small cell lung cancer: An evidence-based guide for the practicing clinican. Philadelphia: WB Saunders Company, 2001, 307
  • 3[3]Ng R, Boer RD, Park A, et al. Non small cell lung cancer(NSCLC): Are elderly patients being under-treated? ASCO Pro,2004, 7118
  • 4[4]Hensing TA, Peterman AH, Schell MJ, et al. The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced, stage ⅢB or Ⅳ nonsmall cell lung carcinoma triated with carboplatin and paclitaxel. Cancer, 2003, 98(4) :779
  • 5[5]Lebitasy MP, Monnet L, Depierre A, et al. Management of elderly lung cancer patients in France: A national prospective survey by the French intergroup of thoracic oncology (WCT).ASCO Pro, 2004, 8163
  • 6[6]Okamoto H, Kudoh H, Nagatomo A, et al. A combination chemotherapy of carboplatin and irinotecan in elderly patients with small cell lung cancer (SCLC). ASCO Pro, 2004, 7212
  • 7[7]FukudaM, Oka M, SoejimaY, etal. Elderly (≥70)smallcell lung cancer (SCLC) chemotherapy: A phase Ⅰ study of carboplatin (CBDCA) and etoposide (VP-16). ASCO Pro,2004, 7217
  • 8[8]Katz AV, Arruda MT, Yamaguchi JY, et al. Comparative retrospective study between brs supportive care (BSC) versus chemotherapy for elderly patients with NSCLC. ASCO Pro, 2004,7355
  • 9[9]Yau T, Asley S, Smith L, et al. Time and chemotherapy treatments trends in the elderly (age 》 70) with lung cancer in a single UK cancer centre. ASCO Pro, 2004, 7128
  • 10[10]The elderly lung cancer vinorelbine Italian study group. Effects of vinorelbine on quality of life and survival of elderly patients with adbanced non-small-cell lung cancer. J Natl Cancer Inst,1999, 91:66

共引文献118

同被引文献10

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部