枸橼酸铁铵在3.0T磁共振胰胆管成像中的应用

Application of Oral Ferric Ammonium Citrate Solution as a Negative Gastrointestinal Contrast Agent in 3.0T Magnetic Resonance Cholangiopancreatography

目的:探讨口服枸橼酸铁铵(ferric ammonium citrate effervescent granules,FAC)在3.0 T磁共振胰胆管成像(MRCP)检查中的临床应用价值。方法:回顾性分析32例口服FAC及20例未口服FAC行MRCP检查的患者图像。以胰胆管的显示情况和胃肠信号消除情况作为评价标准,对MRCP图像质量进行评价及比较。结果:FAC组的MRCP图像胃肠道液体高信号明显减低,对解剖结构及病变的显示均优于未服FAC组。结论:枸橼酸铁铵可有效消除MRCP图像中胃肠液高信号的干扰,明显改善图像质量,对胆胰管病变的诊断有重要的临床应用价值。

Objective To discuss the clinical value of oral ferric ammonium citrate effervescent granules（FAC） in magnetic resonance cholangiopancreatography（MRCP）.Methods Images of MRCP of 32 patients with oral FAC and 20 patients without oral FAC were retrospectively reviewed.The images quality was evaluated according to the presentation of biliary pancreatic structure or urinary tract and the elimination of gastrointestinal fluid signal.The MRCP image quality in both groups was compared with each other.Results With administration of FAC,high signal interference from gastrointestinal was weakened on MRCP image;FAC was much more helpful and valuable in revealing the anatomical structures and abnormal changes than non FAC protocol.Conclusion The use of FAC can effectively suppress gastrointestinal signals artifact and improve image quality significantly in MRCP,and being clinically valuable in diagnosis of biliary tract and pancreatic diseases.