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葡萄糖二酸的生物炼制及应用研究进展 被引量：6

Research progress in preparation and application of bio-refined D-glucaric acid
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摘要 葡萄糖二酸是含有多羟基的二元酸,广泛来源于葡萄糖基物质,可用于可降解聚合物、药物和食品等产品的制备。本文介绍了硝酸氧化、TEMPO氧化等化学法和生物法制备葡萄糖二酸的原理和方法,并综述了其在抗癌及显像剂药物、聚合物等方面的应用。 D-glucaric acid is a dicarboxylic acid containing polyhydroxy.It can be obtained from many glucose-based substances and be used to prepare products of biodegradable polymers,pharmaceuticals and food.In this review,we try to describe the principles and preparation methods of D-glucaric acid in both chemical（nitric acid oxidation and TEMPO oxidation）and biological fields,and review its applications in both pharmaceuticals（anticancer drugs and imaging agents）and polymers.
作者 余作龙 苗江月 曹飞 周佳栋 朱璇 王月霞 韦萍
机构地区 南京工业大学生物与制药工程学院
出处 《化工进展》 EI CAS CSCD 北大核心 2011年第11期2502-2508,2535,共8页 Chemical Industry and Engineering Progress
基金 国家自然科学基金项目(21106063 30600009)
关键词 葡萄糖二酸 葡萄糖 制备 应用 D-glucaric acid glucose preparation application
分类号 TQ031 [化学工程] TQ073.2 [化学工程]
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参考文献64

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共引文献28

同被引文献79

  • 1魏文英,方键,孔海宁,韩金玉,常贺英.金属有机骨架材料的合成及应用[J].化学进展,2005,17(6):1110-1115. 被引量：66
  • 2李伟杰,陆豫.合成3,4-二取代呋喃-2,5-二甲酸的简便方法[J].化学试剂,2006,28(5):309-310. 被引量：10
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引证文献6

二级引证文献24

化工进展
2011年 第11期

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