期刊文献+

谷胱甘肽S转移酶系与年龄相关性白内障的研究进展 被引量:3

Research advances of glutathione S-transferase system and age-related cataract
下载PDF
导出
摘要 白内障是最常见的致盲眼病之一。谷胱甘肽S转移酶(glutathione S-transferases,GSTs)是典型的多功能酶,主要催化各种化学剂与谷胱甘肽结合。近些年的研究表明,GSTs有抗过氧化引起的白内障作用。GSTs表达水平的高低在白内障形成中有着重要的作用。我们将近年来GSTs与年龄相关性白内障的研究情况做一综述。 Cataract is one of the most common eye diseases causing blind,glutathione S-transferases(GSTs) are typical multifunctional enzyme,which can catalyze the combination of various chemical agents and glutathione.Recent studies have shown that GSTs have effect on anti-oxidant which can lead to the cataract.The expression of GSTs plays an important role in the process of cataract formation.This article reviewed the recent advances in the researches on GSTs system and age-related cataract.
作者 李晨 管怀进
出处 《国际眼科杂志》 CAS 2011年第11期1932-1934,共3页 International Eye Science
基金 中国国家自然科学基金资助项目(No.81070718)~~
关键词 谷胱甘肽S转移酶 谷胱甘肽 白内障 glutathione S-transferases glutathione ca-taract
  • 相关文献

参考文献27

  • 1美国公共卫生协会 宋仁元 张亚杰 王维一译.水和废水标准检验法(第15版)[M].北京:中国建筑工业出版社,.430-433.
  • 2Ganea E,Harding JJ.Glutathione-related enzymes and the eye.Curr Eye Res 2006;31(1):1-11.
  • 3Tomoyuki T.Role of glutathione S-transferase in lens under oxidative stress.J Health Sci 2005;51(3):263-271.
  • 4Reinemer P,Dirr HW,Ladenstein R,et al.The three-dimensional structure of class π glutathione S-transferase in complex with glutathione sulfonate at 2.3 A resolution.EMBO J 1991;10(8):1997-2005.
  • 5Strange RC,Spiteri MA,Ramachandran S,et al.Glutathione S-transferase family of enzymes.Mutation Res 2001;482(1-2):21-26.
  • 6Sheehan D,Meade G,Foley VM,et al.Structure,function and evolution of glutathione transferases:implications for classification of non-mammalian members of an ancient enzyme superfamily.Biochem J 2001;360(1):1-16.
  • 7Hayes JD,Strange RC.Glutathione S-transferase polymorphisms and their biological consequences.Pharmacology 2000;61(3):154-166.
  • 8Strange RC,Spiteri MA,Fryer AA,et al.Glutathione-S-transferase family of enzymes.Mutation Res 2001;482(1):21-26.
  • 9Alberti G,Oguni M,Podgor M,et al.Glutathione S-transferase M1 genotype and age-related cataracts.Lack of association in an Italian population.Invest Ophthalmol Vis Sci 1996;37 (6):1167-1173.
  • 10Zigler JS Jr,Huang QL,Du XY.Oxidative modification of lens crystallins by H2O2 and chelated iron.Free Radic Biol Med 1989;7(5):499-505.

二级参考文献5

共引文献14

同被引文献52

引证文献3

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部