中西医结合治疗原发性胆汁瘀积性肝硬化皮肤瘙痒10例

Treating 10 cases of primary biliary cholestasis liver cirrhosis skin pruritus in the integrative medicine

皮肤瘙痒是原发性胆汁瘀积性肝硬化的常见症状,与血胆汁酸浓度增高及机体释放类阿片受体物质有关,对于患者严重瘙痒西医主要治疗为以熊去氧胆酸为主药,保肝退黄基础上,必要时给以抗组胺类药对症止痒治疗,对疗效并不满意,严重影响患者生活质量。

Skin pruritus is a common syndrome of primary biliary cholestasis cirrhosis,relate to the increasing of serum bile acid concentration and the opioid receptor release of body.Treating this disease mainly used ursodeoxycholic acid on the basis of Baogan Tuihuang,gave antihistamines symptomatic antipruritic therapy during nesserary period,but it can not make a better effect and also affected the patients＇ life quality.