经卵巢静脉栓塞介入联合中药治疗盆腔淤血综合征

Ovarian vein embolization combined with TCM for treatment of pelvic congestion syndrome:a pilot study

目的:探讨经卵巢静脉栓塞介入联合中药治疗盆腔淤血综合征的临床效果及可行性。方法:收集番禺疗养院和番禺中心医院60例确诊盆腔淤血综合征的患者,随机分成两组,每组30例,研究组行介入卵巢静脉栓塞加中药治疗,对照组单纯用中药治疗,中药治疗均为3个疗程,观察两组疗效。结果:盆腔淤血征程度,发病年龄两组间差异无统计学意义。两组在治愈率,好转率,未愈率及复发率比较中,差异有统计学意义(P<0.05)。研究组治愈率较对照组高,未愈率及复发率均较对照组低。结论:两组治疗方式中以卵巢静脉栓塞后加用中药治疗初始疗效肯定,远期效果好,复发率低,是目前较好的治疗手段。对照组纯中药治疗费用低廉,不良反应少,治疗方便,但存在疗程长,易复发等弊端。

Objective ：To evaluate the clinical efficacy and feasibility of ovarian vein embolization combined with Traditional Chinese medicine （ TCM ） for treatment of pelvic congestion syndrome （PCS）. Methods ： Sixty patients with PCS confirmed registered to Panyu Sanatorium or Panyu Central Hospital were randomized into treatment group and control group （ n = 30 each）. The treatment group underwent interventional ovarian vein embolization combined with TCM treatment, while the control group was on TCM alone. In both groups,3 courses of TCM were given. The clinical efficacy in both groups was analyzed and compared. Results：There was no significant difference in severity of pelvic congestion and patient age at onset between the two groups. However, statistical differences were noted between groups in number of patients who experienced full recovery, improvement, no response or relapse （ P 〈 0.05 ）. The treatment group showed higher rate of full recovery and lower rate of no response as compared with the control group. Conclusion ： Ovarian vein embolization combining with TCM as an initial treatment of PCS results in definite efficacy, favorable long-term outcomes and less relapse. In contrast, monotherapy with TCM may be less expensive, more patient-compliant and with less side effects, but is also associated with longer course of treatment and higher rate of relapse.