2型糖尿病患者预混胰岛素类似物治疗与持续胰岛素输注治疗剂量的相关性研究

Correlation between the dosage of premixed insulin analogue treatment and continuous subcutaneous insulin infusion treatment in type 2 diabetes

分析经短期持续皮下胰岛素输注（CSⅡ）强化治疗后换为预混胰岛素类似物治疗的2型糖尿病患者，发现CSⅡ治疗末日胰岛素使用量小于45 U／d宜选择每日2次预混胰岛素类似物治疗，大于45 U／d宜选择每日3次预混胰岛素类似物治疗。其治疗剂量可根据以下方程：每日2次预混胰岛素类似物治疗剂量=13．093＋0．395xCSⅡ治疗总量，每日3次预混胰岛素类似物治疗剂量=23．114＋0．405×CSⅡ治疗总量。

To observe the patients with type 2 diabetes who were injected premixed insulin analogues after shb/t time continuous subcutaneous insulin infusion（CSⅡ） treatment. It was found that the patients needed premixed insulin analogue injection 2 times daily when the dosage of CSII was less than 45 U/d, and 3 times daily when the dosage was greater than 45 U/d. The relationship of dosages between premixed insulin analogue treatment （Y） and CSII treatment （X） was calculated by following equations ： 2 times daily premixed insulin analogue treatment ： Y = 13. 093 ＋0. 395X, 3 times daily premixed insulin analogue treatment：Y = 23.114＋0. 405X.