原发性胆汁性肝硬化伴甲状旁腺腺瘤诊治

Appoach to the patient with parathyroid adenoma and primary biliary cirrhosis： diagnosis and treatment

原发性胆汁性肝硬化可从多种途径影响钙和维生素D的代谢，进而引起骨软化和继发性甲状旁腺功能亢进症，但当同时出现低蛋白血症时可掩盖血钙的真实水平。因此若该病合并甲状旁腺腺瘤时容易漏诊。本文详细介绍1例原发性胆汁性肝硬化合并甲状旁腺腺瘤的诊治过程，旨在提醒临床医生重视低蛋白血症对血清总钙水平的影响。

In patient with primary biliary cirrhosis, the metabolism of calcium and vitamin D could be affected and osteomalacia and secondary hyperparathyroidism might oceurr. Besides, hypoalhuminemia may mask the real level of serum calcium and thus lead to misdiagnosis of coexisting parathyroid adenoma. Therefore, a rare case of parathyroid adenoma associated with primary biliary cirrhosis was herewith presented to call attention to the effect of hypoalbuminemia on serum calcium.