禽白血病病毒J亚群诱导蛋鸡群多种肿瘤

Mutipal Tumors Induced by Avian Leukosis Virus Subgroup J in Layer Flock

2009年8月,山东泰安某海兰褐商品蛋鸡场,开产后产蛋率只有60%～70%,31周龄时,死亡率突然增加,最高达20%。患病鸡经大体剖检、病理组织学、PCR和免疫组织化学检测确诊为J亚群禽白血病。病理组织学检测发现送检鸡除了髓细胞瘤外,还存在明显的纤维肉瘤、组织肉瘤、腺癌和血管内皮瘤等肿瘤。纤维肉瘤单独存在,组织肉瘤、腺癌和血管内皮瘤分别和髓细胞瘤混合存在,本文详细描述了各肿瘤的组织学特点。ALV-J从肉种鸡传向商品蛋鸡后引起肿瘤谱扩展的原因和机制值得进一步研究。

In August 2009,low produce peak was observed by farm owner in Hy-line layer chicken flock at Tai′an in Shandong province.The rate of produce only was 60%-70%,and the mortality was up to 20% at age of 31-week.The ill chickens were diagnosed as avian leukosis virus subgroup J infection by gross observation,pathology,PCR and immunohistochemistry.Except myelocytomas,fibrosarcomas,histiocytic sarcomas,intestinal adenocarcinoma and hemangioendothelioma were also observed in same or different organs.Fibrosarcomas exist single in ill chicken,and the other tumors were concurrent with myelocytomas.The histopathology detail characters of tumors were described in this paper.The etiology and mechanism of transmmition and tumor spectrum expended of ALV-J need to be further studied.