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纤溶酶治疗全聋型或接近全聋型突发性聋的疗效观察 被引量:9

Effects of fibrinogenase in treatment of complete or profound sudden deafness
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摘要 目的探讨纤溶酶治疗全聋型或接近全聋型突发性聋的效果。方法将52例患者随机分成两组,对照组主要用长春西汀治疗,治疗组在用长春西汀的基础上加用纤溶酶,均以10天为一疗程。结果治疗组与对照组疗效比较,有效率分别为61.5%和30.8%,显效率分别为38.5%和11.5%,差异有显著性(P<0.05)。结论只要没有用药禁忌症,纤溶酶治疗全聋型或接近全聋型突发性聋是安全的、有效的。 Objective To study the utility of fibrinogenase in the treatment of sudden hearing loss. Methods Fifty-two patients were randomly selected to receive vinpocetine only or vinpaeetine plus fihrinogenase for 10 days. Results The rate of hearing improvement was 61.5% (16/26) in those who received additional fibrinogenase, compared to 30.8% (8/26) in those who received vinpocetine only. The rate of significant improvement in the two groups was 38.5% (10/26) and 11.5% (3/26) respectively (P 〈 0.05). Conclusion Fibrinogenase can improve treatment outcomes in sudden hearing loss when there is no eontraindication
出处 《中华耳科学杂志》 CSCD 2011年第3期300-302,共3页 Chinese Journal of Otology
关键词 突发性聋 纤溶酶 溶栓治疗 Sudden deafness Fibrinogenase Thrombolytic therapy
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