母系遗传药物性耳聋核基因TFB1M研究进展
被引量:2
摘要
线粒体DNA(MitochondrialDNA,mtDNA)突变是导致母系遗传药物性耳聋(Maternalinheritedaminoglyeosidean.tibioticsinduceddeafness.MaternalinheritedAAID)最重要的原因之一,是导致携带此突变的个体对氨基糖甙类抗生素(Aminoglycosideantibiotics,AmAn)高度敏感而使听觉细胞功能障碍继而产生耳聋的主要因素。
出处
《中华耳科学杂志》
CSCD
2011年第3期353-355,共3页
Chinese Journal of Otology
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引证文献2
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1周璐霞,姜惠雪,郑潮钏,唐霄雯,郑斌娇.核修饰基因突变与线粒体基因突变协同致聋[J].生命科学,2018,30(3):302-309.
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