摘要
目的:了解凝固酶阴性的葡萄球菌在血培养中的感染特点和耐药性。方法:应用BacT/ALERT3D进行培养,药敏实验采用K-B纸片扩散法。结果:5172例血培养标本检出病原菌494株,凝固酶阴性葡萄球菌203株,占41.09%;凝固酶阴性葡萄球菌对阿奇霉素、罗红霉素、复方新诺明的耐药率较高,对克林霉素、庆大霉素、阿米卡星、二甲胺四环素、环丙沙星的耐药率较低,未发现万古霉素耐药株,MRCNS的检出率为76.84%。结论:凝固酶阴性葡萄球菌在血液感染中占主导地位;监测其耐药性为临床合理用药提供有力依据。
Objective：To offer the situation of coagulase-negative Staphylococcus（CNS）and its Drug resistance.Methdos：Blood was cultured in BacT/ALERT3D.Antibiotic susceptive test was done by Kirby-Bauer method.Results：290 strains of pathogen were isolated from 3172 samples of blood,and there were 118 strains of CNS accounted for 40.6%.The resistance of CNS to azithromycin,roxithromycin,SMZCO was higher.The resistance to clindamycin,gentamycin,anikacin,minoyclin,ciprofloxacin was lower.None strains was resistant to vancocin.The rate of meticillin-resistant CNS was 76.3%.Conclusions：CNS is the major pathogen in spetice mia.Minoycline is the first choice for treating,but vancocin must be careful
关键词
血培养
凝固酶阴性葡萄球菌
耐药性
Blood culture
Coagulase-negative staphylococcus
Drug resistance
