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骨髓基质细胞移植治疗创伤性脑损伤研究进展 被引量：2

Advances in the Treatment of Brain Traumatic Injury by Transplanting the Bone Marrow Stromal Cells
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摘要 如何改善创伤性脑损伤后神经细胞的再生和神经行为的恢复,一直是困扰神经科医生的一大难题。骨髓基质干细胞具有多向分化潜能,在适宜条件下骨髓基质干细胞可分化为神经元和神经胶质细胞,促进创伤性脑损伤的修复。作用机制主要与替代受损细胞、产生内源性细胞因子和促进内源性神经干细胞增殖有关。虽然仍存在一些尚待解决的问题,但骨髓基质细胞治疗创伤性脑损伤仍是一种很有前途的治疗。 How to improve the regeneration of nerve cells and revival of neurobehavior after brain amage is a puzzle to perplex the in Department of Neurology.Bone marrow stromal cells（BMSCs） can differentiate into multiple cells,such as neurons and astrocyte in a suitable condition,which can promote recovery of Traumatic brain injury（TBI）.The therapeutic mechanism is concerned with replacement of the injured cells and activation of endogenous repairmen and promotion of endogenous neural stem cell proliferation.BMSCs transplantation is a promising treatment of TBI,though there are still some problem unresolved.
作者 赵晓程 韩维 朱玉德
机构地区 内蒙古医学院 内蒙古医学院第三附属医院神经外科
出处 《内蒙古医学杂志》 2011年第8期942-944,909,共4页 Inner Mongolia Medical Journal
关键词 创伤性脑损伤 骨髓基质细胞 细胞移植 Bone marrow stromal cells Bone marrow stromal cells Cell Transplantation
分类号 R655.15 [医药卫生—外科学] R457.7 [医药卫生—治疗学]
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参考文献21

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二级参考文献33

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内蒙古医学杂志
2011年 第8期

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