改良血液透析方法在重症肾综合征出血热治疗中的应用

Application of improved hemodialysis method in treatment of severe hemor rhagic fever with renal syndrome

目的:通过分析临床病例,探讨改良血液透析方法在重症肾综合征出血热治疗中的意义及策略。方法:98例患者应用血液透析治疗,匀速超滤组51例,阶梯超滤组47例,对两组治疗前血浆总蛋白、白蛋白、血尿素氮、血肌酐、心肌坏死标志物、转氨酶等指标进行对比分析,分析不同治疗方法之间的差异。结果:与匀速超滤组比较,阶梯超滤组低血压、肌肉抽搐疼痛等并发症发生率低,出院时血尿素氮及血肌酐值低,肾功能恢复好,差异均有统计学意义(均P<0.05)。结论:阶梯超滤组与匀速超滤组比较,透析并发症少,肾脏功能恢复好,建议临床推广应用。

Objective： To explore the significance and strategies of the improved hemodialysis method in the treatment of severe hemorrhagic fever with renal syndrome by analyzing clinical cases. Methods： 98 patients were given the hemodialysis treatment, among whom 51 patients were selected as the constant velocity ultrafiltration group and 47 patients were selected as the step ultra_filtration group. The plasma total protein, albumin, blood urea nitrogen, serum creatinine, cardiac enzymes, transaminase and other indicators of the two groups before treatment were analyzed comparatively and the differences between the two treatment methods were analyzed. Results： Complications such as incidence rates of low blood pressure, muscle twitches and pain of the step uhrafiltration group were significantly lower than those of the constant velocity ultrafiltration group, blood urea nitrogen and serum creatinine values when discharged of the step uhrafiltration group was significantly lower than that of the constant velocity ultrafiltration group, and renal function recovery of the step ultrafiltration group was significantly better than that of the constant velocity uhrafiltration group （all P〈0.05）. Conclusion： The step uitrafiltration group has fewer dialysis compIications and better renal function recovery compared with the constant velocity ultrafiltration group, thereby worthy of promotion and application.