熊去氧胆酸联合消炎利胆片治疗取石术后胆总管残存结石疗效观察

Effect of Ursodeoxycholic acid and Xiaoyanlidan pill in the treatment of residual billiary stones after ERCP

[目的]观察熊去氧胆酸(UDCA)联合消炎利胆片治疗内镜下逆行胰胆管造影胆管取石(ERCP)术后胆总管残存结石的疗效及机制。[方法]选取2003～2007住院的胆总管结石患者120例,随机分成2组,各60例。2组均行ERCP,术后第2天治疗组患者均口服熊去氧胆酸,常规用量250mg/次,3次/d,消炎利胆片6片/次,3次/d,疗程4周。对照组不予相应治疗。2组皆于术后第1周和第4周行B超检查,记录结石的大小及数目。[结果]治疗组和对照组胆总管结石治愈好转率分别为95.0%、81.7%,差异有统计学意义(P<0.05)。[结论]熊去氧胆酸联合消炎利胆片是治疗ERCP术后胆总管残存结石的有效方法。

[Objective]To investigate the efficacy of Ursodeoxycholic acid（UA）and Xiaoyanlidan pill（XP）in the residual billiary stones after ERCP. [Methods]One hundred and twenty patients were randomly divided into two groups：treatment group and control group,sixty cases in each group.The treatment group was treated with UA and XP after ERCP,while the control group not. [Results]Efficacy in the treatment group and the control group was 95.0% and 81.7% respectively（P0.05）. [Conclusion]UA and XP are effective in the treatment of the residual billiary stones after ERCP.