冠心病血运重建患者再发主要不良心血管事件危险因素的临床研究

A Prospective Clinical Study of Risk Factors Impact on MACCE in the Patients with Coronary Artery Disease

目的探讨冠心病患者接受血运重建后再次发生主要不良心血管事件(MACCE)的危险因素。方法选择于我院接受血运重建治疗的患者为研究对象,记录其临床基本资料、生化指标、冠脉造影及血运重建情况。比较随访期间发生MACCE和未发生MACCE患者上述指标的差异,并采用Logistic回归分析法进行多因素分析,探讨冠心病血运重建患者再发MACCE的危险因素。结果(1)MACCE组老龄(年龄≥65岁)、男性、糖代谢异常、三支病变及MS患者所占比例均高于非MACCE组,差异有统计学意义(P<0.05);(2)Logistic回归分析显示代谢综合征(MS)、三支病变及高龄均为MACCE的危险因素。结论在冠心病血运重建患者中,MS、三支病变及高龄为再发MACCE的危险因素。

Objective We aimed to know the risk factors of major adverse cardiac and cerebral events （ MACCE ） in patients who suffered coronary artery disease （ CAD ）. Methods 860 patients came from the lth People Hospital of Wenling join to the clinical try. The basic document, index of physiolgical chemistry, coronary angiography and revascularization were recorded. The patients who suffered major adverse cardiac and cerebral events （ MACCE ） in the followed period were named the MACCE group, otherwise, were named as the compared group. We compared the above indexes in the two groups, and Logistic Regression Analysis was used to know the risk factor of revascularization in the patients with CAD. Results （ 1 ）The proportion Of the aged, male, abnormal glucose metabolism, three lesions and metabolic syndrome was significantly higher in the MACCE group than that in the compared group （P 〈 0.05 ） ; （ 2 ） The metabolic syndrome （ MS ） , age （ ≥ 65 years old ） and triple vessel disease were risk factors of MACCE. Conclusion The metabolic syndrome （ MS ）, age （ ≥ 65 years old ） and triple vessel disease were risk factors of MACCE in CAD patients.