摘要
An efficient and convenient method for synthesis of 3,5-bis-carbamoyl-2,6-dimethylpyridine derivatives was achieved in good to excellent yields by reaction of anilines with 3,5-bis（3＇,5＇-dimethy1-1＇-pyrazolyl-carbony1）-2,6- dimethylpyridine, in which pyrazoles served as leaving groups. The structures of products were confirmed by spectra data and microanalysis.
An efficient and convenient method for synthesis of 3,5-bis-carbamoyl-2,6-dimethylpyridine derivatives was achieved in good to excellent yields by reaction of anilines with 3,5-bis（3＇,5＇-dimethy1-1＇-pyrazolyl-carbony1）-2,6- dimethylpyridine, in which pyrazoles served as leaving groups. The structures of products were confirmed by spectra data and microanalysis.
基金
Project supported by the National Natural Science Foundation of China （Nos. 20872086, 21072128）, the Leading Academic Discipline Project of Shanghai Municipal Education Commission （No. J50102）, the Foundation of Education Commission of Shanghai Municipality （No. 08zz44）, and the Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry.
