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An Efficient One-pot Synthesis of Pyrazolone Derivatives Promoted by Acidic Ionic Liquid

An Efficient One-pot Synthesis of Pyrazolone Derivatives Promoted by Acidic Ionic Liquid
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摘要 A new class of pyrazolone derivatives has been isolated in good to excellent yields from the 2 : 1 condensation reaction between 3-methyl-1-phenyl-5-pyrazolone and arylaldehydes in the presence of ionic liquid [HMIM]HSO4. The compounds were characterised by their IR, NMR spectra, MS and elemental analyses. The important features of the methodology are a wide application range of substrates, higher yields and shorter reaction time. A new class of pyrazolone derivatives has been isolated in good to excellent yields from the 2 : 1 condensation reaction between 3-methyl-1-phenyl-5-pyrazolone and arylaldehydes in the presence of ionic liquid [HMIM]HSO4. The compounds were characterised by their IR, NMR spectra, MS and elemental analyses. The important features of the methodology are a wide application range of substrates, higher yields and shorter reaction time.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2011年第10期2202-2204,共3页 中国化学(英文版)
基金 Project supported by the National Natural Science Foundation of China (No. 51076174) and the Tianjin National Natural Science Foundation (No. 11JCZDJC21300).
关键词 PYRAZOLE ionic liquid 3-methyl-1-phenyl-5-pyrazolone ALDEHYDES pyrazole, ionic liquid, 3-methyl-1-phenyl-5-pyrazolone, aldehydes
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