原发性胆汁性肝硬化的实验室诊断研究进展

Research progress on laboratory diagnosis of primary biliary cirrhosis

原发性胆汁性肝硬化是一种病因与发病机制至今未明的慢性进行性胆汁淤积性肝脏疾病,且目前尚无治愈的特效方法,早期给予熊去氧胆酸胶囊治疗可以改善肝脏功能,延长生命,一旦进入晚期则需肝移植治疗,所以早期诊断至关重要,本文就实验室诊断的一些新进展进行综述。

Primary biliary cirrhosis（PBC） is a kind of chronic progressive cholestatic liver disease,and has no curative method currently.The etiology and pathogenesis of PBC is still unclear.Ursodeoxycholic acid capsules can improve liver function and prolong life at early stage.Liver transplantation is required at late stage.So early diagnosis is essential.Here we summarize some of the new research progress on laboratory diagnosis of PBC.