2230例变应性疾病患者血清特异性抗体测定分析

Analysis of serum specific IgE in 2 230 patients with allergic diseases

目的检测变应性疾病血清特异性抗体筛选相关过敏原,为临床诊断和治疗提供依据。方法采用过敏原检测系统,对2 230例变应性疾病患者的血清特异性免疫球蛋白E(immunoglobulin,IgE)及总IgE水平进行了检测。结果 2230例变应性疾病患者中过敏原以屋尘螨(28.3%)、粉尘螨(26.6%)为最高,其后依次为蒿(14.9%)、猫毛皮屑(9%)、牛羊肉(9%)、蟑螂(8.3%)、鱼虾蟹(8.1%)、霉菌(6.6%)、牛奶(6.1%)、矮豚草(5.6%)、腰果花生(4.6%)、榆、梧桐、柳、三角叶杨(3.8%)、鸡蛋白(3.8%)、黄豆(3.1%);总IgE阳性率为46.9%。结论血清特异性IgE及总IgE的检测分析可以帮助临床寻找相应过敏原,为变应性疾病的预防、诊断和治疗提供依据。

Objective To detect serum specific IgE in allergic diseases for clinical diagnosis and therapy.Methods The serum specific IgE and total IgE（sIgE） were detected by enzyme immunoassay in 2 230 patients.Results The dermatophagoides farinae（28.3%） and pteronyssinus（26.6%） were the most common allergen in 2 230 patients,followed by Artemisia（14.9%）,cat hair dander（9%）,beef and mutton（9%）,cockroaches（8.3%）,seafood（8.1%）,fungi（6.6%）,milk（6.1%）,short ragweed（5.6%）,peanuts,cashew nuts（4.6%）,elm,sycamore,willow,cottonwood（3.8%）,egg white（3.8%）,soybeans（3.1%）.The positive rate of total IgE was 46.9%.Conclusion The detection of serum specific IgE and total IgE can help to find the corresponding clinical allergy,and provide evidences for prevention,diagnosis and therapy of allergic diseases.