加强下肢动脉硬化闭塞症介入治疗的研究

The interventional therapy for arteriosclerosis obliterans of lower extremities:its current situation and progress

下肢动脉硬化闭塞症(ASO)主要累及髂动脉、股动脉和腘动脉,罹患率逐年增高。跨大西洋多学科共识(TASC)Ⅱ文件的出现,有助于规范治疗选择,使越来越多的患者接受腔内介入治疗。长球囊、长支架的应用提高了介入治疗的疗效。覆膜支架和药物洗脱支架等的出现可能会降低再狭窄的发生率。内膜下成形术及多种新器材的问世,提高了髂股动脉长段闭塞介入治疗的成功率。复合手术在下肢ASO的治疗方面已显示出良好的前景。然而,还有许多问题值得探讨,以进一步提高ASO的疗效。

Arteriosclerosis obliterans（ASO） mainly affects the iliac,femoral and popliteal arteries,and its morbidity is increasing with each passing year.TASC Ⅱ has been helpful in choosing therapeutic method.And more and more patients are willing to accept endovascular interventional treatment.The use of long balloon and long stent has improved the clinical efficiency of interventional therapy.The cover stent and drug eluting stent may most probably decrease the occurrence of restenosis.The success rate of interventional management for long segment iliofemoral artery occlusion has been well improved by new technique and device,such as subintimal angioplasty.Hybrid operation has already shown certain promising outlook in the treatment of ASO in lower extremities.However,there are still many problems which need to be further studied in order to improve the therapeutic results of ASO.