654-2在慢性肺源性心脏病急性发作期的应用研究

Research of chronic cor pulmonale patients during acute period treated with 654-2

目的研究654-2在慢性肺源性心脏病(肺心病)急性发作期的治疗效果。方法将已确诊的100例慢性肺心病急性作期的患者随机分为两组,均给予传统综合疗法,治疗组在传统综合疗法的基础上给予5%葡萄糖注射液+654-2静脉滴注,两组均治疗10 d后观察疗效。结果两组患者治疗后动脉血PaO2、PaCO2比较差异有统计学意义(P<0.05)。对照组总有效率为78.0%,治疗组总有效率为94.0%。结论在传统综合治疗的基础上加用654-2治疗肺心病可使PaO2、PaCO2得到显著改善,明显提高了慢性肺心病急性发作期的治疗效果。

Objective To research the effect of 654-2 used in chronic cor pulmonale patients during acute period. Methods100 chronic cor pulmonale patients were randomly divided into control group and treatment group.100 patients were all given comprehensive therapy,and the treatment group was added 654-2. ResultsThere was statistically significant difference between the control group and the treatment group in PaO2 and PaCO2.The total effective rate of the control group was 78.0%,and of the treatment group was 94.0%. Conclusions 654-2 combined with comprehensive therapy to treat chronic cor pulmonale can improve the level of PaO2 and PaCO2,and improve the curative effect.