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单唾液酸四己糖神经节苷脂治疗新生儿缺氧缺血性脑病临床观察

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摘要 目的观察神经节苷脂对新生儿缺氧缺血性脑病的治疗效果。方法将72例诊断明确的新生儿缺氧缺血性脑病患儿随机分为治疗组和对照组各36例。在常规治疗的基础上,治疗组加用单唾液酸四己糖神经节苷脂,对照组加用脑生素。结果治疗组治疗后脑CT、新生儿神经行为测定评分差异均有统计学意义(P〈0.05)。结论应用单唾液酸四己糖神经节苷脂治疗新生儿缺氧缺血性脑病疗效确切。
出处 《中国实用乡村医生杂志》 2011年第11期61-62,共2页 Chinese Practical Journal of Rural Doctor
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  • 1赵时敏.新生儿缺氧缺血性脑病的防治及研究方向[J].中华儿科杂志,1997,35(2):59-60. 被引量:193
  • 2韩玉昆.新生儿缺氧缺血性脑病诊断依据和临床分度[J].中华儿科杂志,1997,35(2):99-100. 被引量:2786
  • 3[1]Ledeen RW, Wu GS, Lu ZH, et al. The role of GMl and other gangliosides in neuronal differentiation: overview and new finding. Ann N Y Acad Sci 1998, 845: 161-175.
  • 4[2]Silva RH, Bergamo M, Vital BMBF, et al. Effects of neonatal GM1 administration on the discrimination avoidance behavior of adult rats. Ann N Y Acad Sci 1998, 845: 45-53.
  • 5[3]Ando S, Tanaka Y, Waki H, et al. Gangliosides and sialycholesterol as of synaotic functions. Ann N Y Acad Sci 1998, 845:232-239.
  • 6[4]Schengnmd CL, Mummert CM. Exogenous glanglisides: How do they cross the blood-brain barrier and how do they inhibit cell proliferation? Ann N Y Acad Sci 1998, 845:279-283.
  • 7[5]Frontczak-Baniewicz M, Gadasmki R, Barskov 1, et al. Beneficial effects of GM1 ganglioside on photochemically-induced microvascular injury in cerebral cortex and hypophysis in rat.Exp Toxicol Pathol, 2000, 52(2): 111-118.
  • 8[6]Simon RP, Chen J, Graham SH. GM1 ganglioside treatment of focal ischemia: a dose-response and microdialvsis study. J Pharmacol Exp Ther 1993, 265(1): 24-29.
  • 9[7]Krajnc D, Wemlinger TA, Neff NH, et d. Neonatal hypoxia:early neurotransmitter responses and the consequences of treatment with GM1 ganglioside. J Pharmacol Exp Ther 1994, 271(3): 1299-1306.
  • 10[8]Garofalo L, Cuello A. Nerve growth factor and the monosialoganglioside GM 1: analogous and different in vivo effects on biochemical, morphological, and behavioral paramenters of adult cortically lesioned rats. Exp Neurol 1994, 125: 195-217.

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