ET-743,现代海洋药物研究的成功典范

ET-743,a successful story of modern marine drug research

在历经了最初的憧憬和随后的低潮之后,伴随着现代波谱技术、现代色谱技术和现代生物技术的发展,海洋药物研究终于呈现出勃勃生机。ET-743作为最新上市的软组织肉瘤治疗药物,成为现代海洋药物研究的成功典范。本文通过综述ET-743发现的关键研究步骤,旨在向读者简要介绍现代海洋药物研究的技术方法、一般过程以及面临的问题。

With the development of modern techniques in spectroscopy,chromatography and biology,marine drug research is booming after experiencing the initiatory excitation and subsequent downturn.ET-743 is regarded as a successful story of modern marine drug research.This review summarizes the key steps in the discovery of ET-743,aiming to give the readers a brief view on the related techniques,general progress,and possible difficulties.