摘要
心房颤动(atrial fibrillation,AF)是老年人最常见的心律失常,是脑卒中的重要独立危险因素。华法林是防治房颤并发脑卒中最有效的方法,但是华法林的出血并发症的发生率高和需要经常监测凝血指标,临床应用受到限制。近年来研发了一些新的抗凝血药物,其中有的经初步临床应用表明,其疗效与华法林相当,且更安全。本文就新型抗凝药物的研究进展作简要的介绍。
Atrial fibrillation（AF） is the most common cardiac arrhythmia in elderly patients and an important independent stroke risk factor.Warfarin is most effective for stroke prevention and treatment in patients with AF.Due to the high risk of bleeding and routine laboratory monitoring,the utilization of warfarin is limited.In recent years,there are many ongoing searches for alternative anticoagulants,some of which are more effective,convenient and safer than warfarin.The article introduces the overview of new anticoagulants.
出处
《药学服务与研究》
CAS
CSCD
2011年第5期382-385,共4页
Pharmaceutical Care and Research
关键词
药物疗法
心房颤动
脑血管意外
抗凝药
综述
drug therapy
atrial fibrillation
cerebrovascular accident
anticoagulants
review
