摘要
AIM:To investigate the antioxidant activity and total phenolic content from the crude extracts and crude fractions of ten species of Phellinus mushrooms collected from northeast Thailand.METHODS:The samples were tested for their radical scavenging activity toward 2,2-diphenyl-1-pricylhydrazyl (DPPH) radical (DPPH method) and total phenolic content (Folin-Ciocalteu method).RESULTS:Some of the investigated extracts exhibited potent radical scavenging activity with the IC 50 ranging from (7.30±0.34) to (19.80±0.13) μg·mL-1.IC 50 were in the range of the standard antioxidant used;quercetin,ascorbic acid and butylated hydroxytoluene (BHT).The strongest scavenging activity as comparable to quercetin was found in the crude 80% EtOH extract of P.torulosus.The crude EtOAc fraction of P.pini showed the highest total phenolic content with a value of 87.76±1.00 equivalent gallic acid (EGA) while the samples with potent antioxidant activity were also determined to have high amount of total phenolics (78.34±0.27 to 51.01±0.38) EGA.CONCLUSION:These results indicated that crude extracts from Phellinus mushrooms have a potential to be natural antioxidant source.
AIM：To investigate the antioxidant activity and total phenolic content from the crude extracts and crude fractions of ten species of Phellinus mushrooms collected from northeast Thailand.METHODS：The samples were tested for their radical scavenging activity toward 2,2-diphenyl-1-pricylhydrazyl （DPPH） radical （DPPH method） and total phenolic content （Folin-Ciocalteu method）.RESULTS：Some of the investigated extracts exhibited potent radical scavenging activity with the IC 50 ranging from （7.30±0.34） to （19.80±0.13） μg·mL^-1.IC 50 were in the range of the standard antioxidant used;quercetin,ascorbic acid and butylated hydroxytoluene （BHT）.The strongest scavenging activity as comparable to quercetin was found in the crude 80% EtOH extract of P.torulosus.The crude EtOAc fraction of P.pini showed the highest total phenolic content with a value of 87.76±1.00 equivalent gallic acid （EGA） while the samples with potent antioxidant activity were also determined to have high amount of total phenolics （78.34±0.27 to 51.01±0.38） EGA.CONCLUSION：These results indicated that crude extracts from Phellinus mushrooms have a potential to be natural antioxidant source.
出处
《中国天然药物》
SCIE
CAS
CSCD
北大核心
2011年第6期441-445,共5页
基金
supported by Center of Excellence for Innovation in Chemistry (PERCH-CIC) and Faculty of Science,Mahasarakham University
