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焦虑障碍脑影像学研究进展 被引量：3

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摘要 来自动物、临床和神经影像学对焦虑神经环路的研究证据表明,在经典的Pavlovian恐惧条件反射动物模型研究基础上,人类的病理性焦虑和动物的恐惧条件反应应答有着类似的脑神经环路,恐惧条件反射神经机制在不同物种之间存在高度保守性和一致性,本文对焦虑障碍的神经环路脑像学研究进行探讨。
作者 张燕 陆邵佳 廖梅 李凌江
机构地区 中南大学湘雅二医院
出处 《国际精神病学杂志》 2011年第4期237-241,共5页 Journal Of International Psychiatry
基金 国家自然科学基金(30830046) 973课题(2009CB918303) 教育部博士点基金(20090162110011) 湖南省自然基金(10JJ6034) 湖南生卫生厅基金(B2009024)
关键词 焦虑障碍 功能核磁共振 弥散张量成像
分类号 R749.7 [医药卫生—神经病学与精神病学]
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参考文献15

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同被引文献36

  • 1Reiman EM. The application of positron emission tomography to the study of normal and pathological emotions. Journal of Clinical Psychiatry, 1997 ; 58 (16) : 4 - 12.
  • 2Sean N, Lagopoulos J, Daniel F, et al. Correlating anterior insula gray matter volume changes in young people with clini- cal and neurocognitive outcomes: an MRI study. Animal Sci- ence and Biotechnology, 2012 ; 45 (12) : 1-10.
  • 3.蔡泽龙,马树华.广泛性焦虑障碍负性情绪抑制障碍与负性情绪启动下事件相关fMRI研究.眉际医学放射学杂志,2012;34(6):515-517.
  • 4Fonzo GA, Ramsawh HJ, Flagan TM, et al. Cognitive-behavior- al therapy for generalized anxiety disorder is associated with attenuation of limbic activation to threat-related facial emo- tions. Journal of Affective Disorders, 2014 ; 169 : 76- 85.
  • 5Uchida RR, Del-Ben CM, Busatto GF, et al. Regional graymatter abnormalities in panic disorder: a voxel- based mor- phometry study. Psychiatry Research, 2008 ; 163 ( 1 ) : 21- 29.
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  • 7Zhang Y, Duan L, Liao M, et al. MRI for brain structure and function in patients with first-episode panic disorder. Medical Sciences, 20 l 1 ; 36 (12) : 1170-1175.
  • 8Wittmann A, Schlagenhauf F, Guhn A, et al. Anticipating ag- oraphobic situations:the neural correlates of panic disorder with agoraphobia. Eur Arch Psychiatry Clin Neurosci ,2014;44 ( 11 ) :2385-2396.
  • 9Bruhl AB, Hanqqi J, Baur V, et al. Increased cortical thick- ness in a frontoparietal network in social anxiety disor- der. Human Brain Mapping, 2014 ; 35 (7) : 2966-2977.
  • 10Sven CM, Aouidad A, Gorodetsky E, et al. Gray matter vol- ume in adolescent anxiety:An impact of the brain-derived neurotrophic factor val met polymorphism. Amercian Acade- my. 2013 ;52(2) : 184-195.

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国际精神病学杂志
2011年 第4期

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