银屑病愈后复发与外周血T淋巴细胞关系研究

Relation research of recurrence of psoriasis after more and peripheral blood T lymphocytes

目的:观察银屑病患者临床痊愈时外周血T淋巴细胞亚群的情况,及其与近期病情复发的关系。方法:应用流式细胞分析法在患者痊愈时进行检测,并观察其30周内病情是否复发。结果:患者痊愈时,外周血CD8+T细胞相比正常组明显减低;复发组CD4+T细胞较未复发组明显减低。结论:银屑病患者痊愈时仍存在细胞免疫功能的异常。痊愈时CD4+T细胞较低者近期复发的可能性更大。

Objective： To investigate the relationship between the recurrence and T cells in peripheral blood of the cured psoriasis patients.Methods： To test the cured patients with the flow cytometry and observe the recurrence in 30 weeks. Results： In contrast to the healthy group,CDS＋T is significant lower（P〈0.05）. CD4＋T of the recurrence group is much lower than the remission group （ P〈0.05 ） .Conclusion： The immunologic function of the cured patients is still abnormal. The patients with lower CD4＋T may have a higher probability of relapse.