啤酒及硒对荷瘤小鼠的抗氧化作用

Beer and selenium anticancer effect in mice with tumor

目的:探讨金川保健啤酒、啤酒加硒及硒对荷瘤小鼠的抗氧化作用。方法:用硒、啤酒及啤酒加硒饲养小鼠,通过测定血清丙二醛(MDA)、肝匀浆超氧化物歧化酶(SOD)及乳酸脱氢酶(LDH)来判定啤酒、啤酒加硒及硒对荷瘤小鼠的抗氧化作用。结果:啤酒组、啤酒加硒组及硒组荷瘤小鼠丙二醛(MDA)和乳酸脱氢酶(LDH)明显小于对照组,而超氧化物歧化酶(SOD)明显大于对照组。结论:金川保健啤酒、啤酒加硒及硒对荷瘤小鼠均有明显的抗氧化作用,并能降低其体内乳酸脱氢酶。

Objective： To study the antioxidant effect of selenium, jinchuan health beer and the combination of selenium and beer in mice with tumor. Methods： the mice were fed with selenium, beer and the combination of selenium and beer, we decided antioxidant effect by determining the serum malondialdehyde（MDA）, liver superoxide dismutase（SOD）, lactate dehydrogenase（LDH）. Results： the serum malondialdehyde（MDA） and lactate dehydrogenase（LDH） in Se group, beer group and the combination of selenium and beer group were significantly lower than those of the control group（P〈0.05）, The liver superoxide dismutase（SOD） in group Se, beer and the combination of selenium and beer was higher than that of the control group（P〈0.01）. Conclusion： Selenium, beer and the combination of selenium and beer shows good antioxidant effect, reduce the lactate dehydrogenase（LDH） in vivo.