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胃癌组织中HER2蛋白的表达变化及意义 被引量:3

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摘要 目的观察胃癌组织中HER2蛋白的表达变化,并探讨其临床意义。方法采用免疫组化法检测85例胃癌组织、癌周胃组织及正常胃组织中的HER2蛋白。结果 HER2蛋白在胃癌组织中、癌周胃组织及正常胃组织中的过表达率分别为23.5%、3.5%、0,前者明显高于后两者(P均<0.05)。HER蛋白过表达与胃癌的位置、Lauren分型、临床分期有关(P均<0.05)。结论胃癌组织中HER2蛋白过表达,检测HER2有助于胃癌的预后判断。
作者 寸英丽 查勇
出处 《山东医药》 CAS 北大核心 2011年第42期72-73,共2页 Shandong Medical Journal
基金 云南省自然科学应用基础研究基金资助项目(2010CD179)
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