摘要
本文调查长沙地区25万城乡人群支气管哮喘患病情况,发现患病率为0.79%,有阳性家族史者占64.79%,对其中672例哮喘患者的19206名亲属的家谱进行调查,结果患病率为12.06%、男性为10.33%、女性为14.01%,患者各级亲属患病率均高于群体患病率。患病率与亲缘关系明显。不同类型哮喘的各级亲属患病率比较:外源性发病率高于内源性。哮喘病是一种遗传性疾病,遗传方式主要是多基因遗传。
An investigation on the prevalence of asthma in a population of 253860 in Changsha urban and rural atreas. The prevalence was 0.79%, 64.79% of 2002 patients with a positive family history of asthma were found.The relationship between bronchial asthma and genetics was studied through a population of 19 206 from 672 family cases. The prevalence of family cases was 12.06%(10.33% in male, 14.01% in female). There was significant difference between the family case population and the general population. Also, significant differences between each grade of family cases were noted. The extrinsic prevalence was higher than the intrinsic prevalence in the family cases.Bronchial asthma is a hereditary disease. The important pattern is multifactorial inheritance.
出处
《遗传与疾病》
CSCD
北大核心
1990年第3期147-149,189,共3页
关键词
支气管哮喘
多基因遗传
Bronchial asthma Multifac torial inheritance
