早期自然流产绒毛染色体研究

CHROMOSOME STUDIES OF EARLY SPONTANEOUS ABORTIONS

作者采用直接法研究了60例早期自然流产和30例人工流产绒毛细胞染色体。结果发现,难免流产组染色体异常率明显高于先兆流产组和人工流产组,差别显著(P<0.05)。说明部分难免流产的原因与胚胎染色体异常有关。作者就早期流产中染色体异常发生率及类型,直接法用于早期流产绒毛染色体检查的可行性和临床应用价值进行了探讨。

60 early spontaneous abortions and 30 early artificial abortions were studied by analysing chromosome directly from chrionic villi. Significantly more cases of abnormal karyotyes were observed among the inevitable abortions (P<0.05). It is concluded that chromosome anomalies in the fetus is a cause of part of inevitable abortions. The aims of the present study are to estimate the frequency and types of chromosomally abnormal abortuses in early spontaneous abortion and to evaluate the significance of analysing chromosome directly from chorionic villi in clinical practice.