系统性纵隔淋巴结清扫在非小细胞肺癌手术中的应用

Application of systematic mediastinal lymphadenectomy in surgery for non-small cell lung cancer

目的:探讨系统性纵隔淋巴结清扫术在非小细胞肺癌治疗中的作用。方法:回顾1995年1月～2006年5月手术切除的Ⅰ～Ⅲa期非小细胞肺癌136例,其中传统肺癌根治术68例,自2002年后所有肺癌行根治加系统纵隔淋巴结清扫术68例,比较两组术后并发症发生率及5年生存率。结果:传统肺癌根治术后并发症发生率及5年生存率分别为11.2%、21.0%,而系统性纵隔淋巴结清扫术后并发症发生率及5年生存率分别为12.7%、44.4%。结论:系统性纵隔淋巴结清扫术提高了患者的5年生存率,术后并发症发生率未增加。

Objective： To discuss application of systematic mediastinal lymphadenectomy in the treatment of non-small cell lung cancer.Methods： Clinical data of 136 non-small cell lung cancer cases at stage Ⅰ～Ⅲa who were admitted from January 1995 to May 2006 years and underwent surgery were analyzed retrospectively.68 cases had traditional radical operation and another 68 cases had systematic mediastinal lymphadenectomy after radical surgery.Incidence of postoperative complication and 5-year survival rate were observed and compared.Results： Morbidity and the 5-year survival rate were 11.2% and 21.0% in traditional group,while the rate were 12.7% and 44.4% in systematic mediastional lymphadenectomy group.Conclution： Systematic mediastinal lymphadenectomy improves the 5-year survival rate,but can not increase the incidence of postoperative complications.