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紫外分光光度法测定盐酸奈必洛尔片的含量

Determination of nebivolol hydrochloride tablets by ultraviolet spectrophotometry
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摘要 目的:建立盐酸奈必洛尔片剂含量的紫外分光光度测定法。方法:采用紫外分光光度法,以0.1mol/mL盐酸为空白对照,280nm为测定波长,测定盐酸奈必洛尔片的含量。结果:盐酸奈必洛尔在20.32~60.96μg/mL范围内线性关系良好(r=0.999 9,n=5),平均加样回收率为100.9%,RSD为1.14%(n=6)。结论:该方法操作简便、精密度好、结果可靠,适用于盐酸奈必洛尔片含量的快速测定。 Objective: To establish ultraviolet spectrophotometry method for the determination of nebivolol hydrochloride tablets.Methods: The content of nebivolol hydrochloride were determined at 280 nm with 0.1 mol/mL hydrochloric acid as the blank control by ultraviolet spectrophotometry.Results: The nebivolol hydrochloride concentration was in the range of 20.32-60.96 μg/mL,and had a good linear relationship(r=0.999 9,n=5),the average recovery was 100.9% with the RSD of 1.14%(n=6).Conclusions: This method is simple,of good precision.It is reliable rapid determination method for nebivolol hydrochloride tablets.
出处 《海南医学院学报》 CAS 2011年第12期1708-1710,共3页 Journal of Hainan Medical University
基金 海南医学院科研基金资助学报项目(0020110473)~~
关键词 紫外分光光度法 奈必洛尔 含量测定 Ultraviolet spectrophotometry Nebivolol hydrochloride
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