摘要
采用液相合成法,以DCC/HOBt作缩合试剂,合成了新型含二茂铁Statine化合物FcCO-NH-Val-Statine-Phe-Val-OMe,用IR、1HNMR、MALDI-TOF MS、元素分析进行了结构表征,分析了其波谱数据,抑菌实验表明其在浓度为5×10-4mol/L时,对米曲霉抑制率为29.4%。
A novel conjugate of ferrocene with Statine was designed and synthesized by coupling reaction using the standard N, N＇-dicyclohexylcarbodiimide （DCC） and 1-hydroxybenzotriazole （HOBt） protocol. The target compound was characterized by IR,^1HNMR,MS and elemental analysis and the spectroscopic data of the target compound was fully analyzed. The target compound（ with a concentration of 5×10^-4mol/L） was screened against the tested bacteria（Aspergillus oryzae） with 29.4% inhibition.
出处
《化学试剂》
CAS
CSCD
北大核心
2011年第11期1039-1041,共3页
Chemical Reagents
基金
云南省教育厅科学研究基金资助项目(2010Y431)
