肺炎支原体感染与儿童哮喘关系的探讨

Correlation between Mycoplasma pnenumonia infection and pediatric asthma

目的探讨肺炎支原体感染与儿童支气管哮喘的相关性。方法选取96例儿童支气管哮喘患儿作为观察组,87例健康体检者作为对照组,对两组患儿血清MP-IgM进行检测;将观察组分为MP-IgM阳性组与阴性组,对两组患儿血清总IgE水平和外周血嗜酸性粒细胞计数进行比较。结果观察组MP-IgM阳性率为44.8%,显著高于对照组的19.5%,差异有统计学意义(P<0.05);MP-IgM阳性组血清总IgE水平和外周血嗜酸性粒细胞计数显著高于MP-IgM阴性组,差异有统计学意义(P<0.05)。结论肺炎支原体感染与儿童支气管哮喘密切相关。

OBJECTIVE To explore the correlation between Mycoplasma pnenumonia infection and pediatric asthma. METHODS A total of 96 cases pediatric asthma were selected as the observation group and 87 cases healthy people were set as control group.MP-IgM was detected between groups.The patients of observation group were divided into MP-IgM positive group and MP-IgM negative group,the levels of serum total IgE and PBEC counts were compared. RESULTS MP-IgM positive rate was higher in the observation group（44.8%）than that of control group（19.5%）（P〈0.05）.The levels of serum total IgE and PBEC counts were higher in the observation group than that of control group（P〈0.05）. CONCLUSION There is close relationship between M.pnenumonia infection and pediatric asthma.