摘要
HF是各种慢性肝病的共同病理学基础,也是肝硬化的必经阶段。积极的抗HF治疗可以控制多种肝组织疾病,尤其是肝硬化的病理进程。靶点明确、疗效显著的抗HF药物是治疗的首选。本研究从HF药物作用靶点、药物研究的体内外模型及药物研究3个方面展开阐述抗HF药物的最新研究进展。
Hepatic fibrosis were a collective pathology foundation of diversified chronic liver diseases and an indispensable stage of cirrhosis. Active anti-fibrotic therapy may control pathological process of various liver diseases, especially cirrhosis. Yet the first choice of treatment were anti-hepatic fibrosis drugs of specific target and prominent effect. In this review, this study focus on hepatic fibrosis drug targets, research model in vivo/vitro and drug research of fibrosis to elaborate the latest progress of anti-hepatic fibrosis drug.
出处
《中国医药科学》
2011年第20期28-31,共4页
China Medicine And Pharmacy
基金
福建省科技计划项目(2010Y0036)
关键词
肝纤维化
作用靶点
体内外模型
药物研究
Hepatic fibrosis
Target
Research model in vivo/vitro
Drug research
