血清锌含量对脑梗死患者的临床意义

The clinical significance of serum zinc levels for patients with cerebral infarction

目的探讨血清锌含量对脑梗死患者的临床意义。方法选取48例脑梗死患者作为研究组,根据NIHSS评分和MRS分别给予评分;选取40例短暂性脑缺血发作者作为对照组,两组患者均抽取空腹血测定血清锌水平。结果脑梗死组锌平均含量为(0.68±0.29)mg/L,TIA组锌平均含量为(0.76±0.18)mg/L,脑梗死组低于短暂性脑缺血发作组(P<0.05)。脑梗死预后差的患者中锌含量为(0.63±0.27)mg/L,而预后较好的患者锌含量(0.73±0.25)mg/L,预后差者低于预后较好者(P<0.05)。NIHSS评分≤8和锌≤65mg/L与预后不良有关联(P<0.05)。结论血清锌的降低与脑梗死预后密切相关,且能够较准确判定患者的预后及生存质量。

Objective To investigate the clinical significance of serum zinc levels for patients with cerebral infarction. Methods Forty-eight patients with cerebral infarction were used as the study group, according to the NIHSS score and MRS scale .The patients were given score. Forty patients with transient ischemic attack （TIA） as the control group, in two groups fasting blood serum zinc levels were detected. Results the average zinc content of cerebral infarction group were （0.68 ± 0.29） mg / L, average zinc content of TIA group were （0.76 ± 0.18） mg/L, the difference between two groups were statistically significant （P 0.05）. In patients with poor prognosis in cerebral infarction group zinc content was （0.63 ± 0.27） mg/L, and in patients with better prognosis zinc content was （0.73 ± 0.25） mg/ L, the difference between two groups were statistically significant （P 0.05）. NIHSS score ≤ 8 and the zinc ≤ 65mg/L were closely related with the poor prognosis, the differences were statistically significant. （P 0.05）. Conclusion The readuction of serum zinc were closely related to the prognosis of cerebral infarction, and can more accurately determine the prognosis and quality of life.