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舌下含服不同剂量的米索前列醇配伍盐酸丁卡因胶浆用于人工流产手术的临床观察 被引量:1

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摘要 目的探讨人工流产手术中,舌下含服米索前列醇的最佳剂量,缩短手术时间,降低药物副作用,达到松弛宫颈,减轻疼痛程度的目的。方法选用600例自愿要求人工流产,年龄20~40岁、无禁忌证、妊娠45~63d的妇女,随机分成A、B、C三组,A组术前30min舌下含服米索前列醇100μg,吸宫前2min宫颈管内注入盐酸盐酸丁卡因胶浆5mL,B组,术前60min舌下含服米索前列醇200μg,吸宫前2min宫颈管内注入盐酸盐酸丁卡因胶浆5mL,C组术前120min舌下含服米索前列醇400μg,吸宫前2min宫颈管内注入盐酸盐酸丁卡因胶浆5mL。结果三组术中镇痛,宫颈松弛度差异无统计学意义,A组阴道出血,恶心明显低于B、C组,统计学有显著差异。结论人工流产术前舌下含服米索前列醇100μg联合盐酸丁卡因胶浆,具有剂量少,手术等待时间短,其松弛宫颈及镇痛效果好,术前阴道出血,恶心等副反应小等优点。
出处 《中国医药指南》 2011年第29期255-257,共3页 Guide of China Medicine
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