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基层医院盐酸米诺四环素软膏辅助治疗慢性牙周炎36例临床疗效 被引量:2

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摘要 目的观察盐酸米诺四环素(MINO)软膏治疗慢性牙周炎的临床疗效,探讨使用价值。方法 36例慢性牙周炎患者共103颗患牙,采用自身对照法将103颗患牙随机分为两组,对照组51颗患牙给予常规牙周治疗,观察组52颗患牙采取基础牙周治疗+局部应用盐酸米诺四环素软膏,于治疗前、治疗后第4周、停药后2周记录两组患牙的MD、PPD、GI、SBI、PLI、AL、牙周袋底根面附着菌斑的微生物学检查。结果用药后第4周,观察组的MD、PPD、GI、AL、菌斑中杆菌所占的比例均明显优于对照组(P<0.05);停药后第2周,观察组的MD、PPD、GI、SBI、AL、PLI、菌斑中杆菌所占的比例均明显优于对照组(P<0.05)。结论在常规牙周治疗基础上,局部使用盐酸米诺四环素软膏治疗慢性牙周炎疗效确切、操作简便、费用合理,具备在基层医院推广使用的价值。
作者 邹美芬
出处 《中国医药指南》 2011年第30期146-147,共2页 Guide of China Medicine
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