2008至2010年某地区细菌性阴道病的病原菌及其耐药性研究

Research on Pathogen of Bacterial Vaginal Disease and Its Drug Resistance in A District during 2008 to 2010

目的通过对东莞地区178例细菌性阴道病(BV)患者和56例非细菌性阴道病(NBV)患者的阴道加德纳菌(GV)检测结果的比较,以及进行阴道加德纳菌的药物敏感试验,从而探讨引起东莞地区BV的主要病原菌,通过耐药性研究为临床更好的选择药物提供依据。结果 BV患者组3种方法检测到的GV都高于NBV患者组;东莞地区GV对万古霉素、头孢曲松、呋喃唑酮的敏感性较高。结论阴道加德纳菌是引起东莞地区细菌性阴道病的主要病原菌。

Objective The comparison between the testing result of gardnerella vaginalis （GV） in 178 bacterial vaginosis （BV） patients of Dongguan and 56 non-bacterial vaginosis（NBV） patients of Dongguan as well as the drug susceptibility test of gardnerella vaginalis is aiming at finding the better medication for the main pathogens of BV in Dongguan by the research on its drug resistance. Methods The first one is to make the GV test of BV patients and NBV patients by three ways, namely tracing for clue cells, BV test and GV culture and make a comparison of the results. The second one is to make the sensitivity test of 72 sets of GV on 10 types of conventional antibiotics by Kirby-Bauer test. Result The GV counts in the BV patients of three testing methods are high than the NBV patients’; GV is more sensitive to vancomycin, ceftriaxone, furazolidone in Dongguan. Conclusion The main cause of bacterial vaginosis is gardnerella vaginalis in Dongguan.