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格列齐特缓释片对老年初诊2型糖尿病病人的疗效观察 被引量:3

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摘要 目的:观察格列齐特缓释片(达美康缓释片)每日一次对老年初诊2型糖尿病患者血糖控制达标的疗效。方法:83例老年初诊2型糖尿病患者进行格列齐特缓释片(达美康缓释片)治疗一年,比较患者治疗前后糖代谢、胰岛素敏感性、脂代谢、低血糖、体重指数及依从性的变化。结果:治疗后患者血糖降低、糖化血红蛋白降低、胰岛素敏感性明显改善,与治疗前比较,差异有统计学意义(p〈0.05);血脂水平、体重指数较治疗前也有所下降,但差异无统计学意义(p〉0.05),治疗过程无严重低血糖发生。结论:对于初诊老年2型糖尿病患者,以格列齐特缓释片(达美康缓释片)作为起始治疗药物能更利于患者。
作者 王蜀鄂
出处 《中国中医药咨讯》 2011年第21期57-58,共2页
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参考文献11

  • 1American Diabetes Association. Clinical Practice Recommendations 2006. Diabetes Care. 2006;29:s43-s48.
  • 2安雅莉,高妍,朱倩,宁光,贾伟平,黄勤,许雯,李成江,周智广,施秉银,单忠艳,陈璐璐,许樟荣,王姮,严励,钟惠菊,姬秋和,李红,薛元明,张木勋,谷卫,郭晓蕙,高蕾丽,洪洁,刘芳,邹大进,李延兵,张小英,李桢,郭辉,赵晓娟,吴汉妮,王玉珍,赵维纲,张少玲,吴静,张南雁,杨凤英,张云,周鑫荣,任跃忠,李光伟,无.中国新诊断2型糖尿病胰岛素分泌和胰岛素抵抗特点调查[J].中华内分泌代谢杂志,2008,24(3):256-260. 被引量:82
  • 3Festa A,WiUiams K,D'Agostino R,etal.The natural course of β-cell function in nondiabetic and diabetic individuals.The Insulin Resistance Atherosclerosis study.Diabetes.2006;55:l 114-1120.
  • 4中华医学会内分泌学会.中华内分泌代谢杂志,2011,:371-374.
  • 5Zimmet P,Alberti KG,Shaw J. Global and societal implications of the diabelesepidemic. Nature. 2001;414:782-787.
  • 6Wei M,Gaskill SP,Haffner SM,Stern ME Effects of diabetes and level ofglycemia on all-cause and cardiovascular mortality,The San Anlonio Heart Study.Diabetes Care. 1998;21:1167 - 1172.
  • 7Morrish NJ;Wang SL,Stevens LK,Fuller JH. Keen H. Mortality and causes of death in lhe WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia. 2001;44(suppl 2):S14-s21.
  • 8The Diabetes Control and Complications Trial Research Group. The effect of ntensive treatment of diabetes on the development and progression Of long'term complications in insulin dependent diabetes mellitus. N Eng J Med. 1993;329:977-986.
  • 9UK Prospective Diabetes Study (UKPDS)Group. Intensive blood-glucose control with sulphonylureas or insulin compared wilh conventionaI treatment and risk of complications in patients with type 2 diabetes(UKPDS 33)Lancet. 1 998;352:837-853.
  • 10UK Prospective Diabetes Study(UKPDS)Group. Effect of intensive blood-glucose control with mefformin on complications in ovenweight patients with type 2 diabetes (UKPDS 34), Lancet. 1998;352: 854-865.

二级参考文献14

  • 1庞璨,贾伟平.空腹血糖和胰岛β细胞功能的关系[J].中华内分泌代谢杂志,2006,22(4). 被引量:16
  • 2Osei K, Rhinesmith S, Gaillard T. Impaired insulin sensitivity, insulin secretion, and glucose effectiveness predict future development of impaired glucose tolerance and type 2 diabetes in pre-diabetic African Americans. Diabetes Care,2004,27 : 1439-1446.
  • 3Li GW, Lillioja S, Peter H, et al. Introduction of a new index of insulin sensitivity. In proceedings of the 15^th international Diabetes Federation Congress, Kobe, Japan, 1994. (Abstract) 1994, p489.
  • 4Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and β cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 1987,28: 412.
  • 5Haffner SM, Miettinen H, Gaskill SP, et al. Decreased insulin secretion and increased insulin resistance are independently related to the seven risk of non-insulin dependent diabetes meUitus in Mexican Americans. Diabetes, 1995,44 : 1386,1995.
  • 6Weyer C, Bogardus C, Mott DM, et al. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest, 1999,104:787-794.
  • 7Lebovitz HE. Type 2 diabetes: an overview. Clin Chem, 1999,45: 1339-1345.
  • 8Zavaronl I , Bonini I. Hypefinsulinemia in a normal population as a predictor of non-insulin-dependent diabetes meUitus: the Barilla factory revisited. Metabolism, 1999,48:984-994.
  • 9Tripathy D , Carisson M. Insulin secretion and insulin sensitivity in relation to glucose tolerance. Diabetes,2000,49:975-980.
  • 10杨兆军,张波,陈燕燕,王瑶,王昕,赵芳,李光伟.短期胰岛素泵强化治疗对新诊断2型糖尿病患者胰岛素分泌和敏感性的影响[J].中华内分泌代谢杂志,2008,24(2):126-128. 被引量:45

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