摘要
慢性阻塞性肺疾病是一种发病机制尚不明确，呈进行性发展，可以预防的慢性疾病；慢性阻塞性肺疾病的易感性与基因、环境等因素有关。本文将近年来慢性阻塞性肺疾病发病中基因与环境、基因与基因之间相互影响的结果及基因多态性在临床的应用前景作一综述。
Chronic obstructive pulmonary disease （COPD） is a complex disease with multiple pathogenesis components which showing progressive development and can be prevented. The development of COPD has a relationship with genetic susceptibility. This review explores the susceptibility and protecting genes in COPD patients, also the clinical applications of polymorphism.
出处
《国际呼吸杂志》
2011年第20期1568-1572,共5页
International Journal of Respiration
关键词
慢性阻塞性肺疾病
基因易感性
Chronic obstructive pulmonary disease
Gene susceptibility
