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丁螺环酮治疗氯丙嗪引起男性性功能障碍的疗效观察 被引量:4

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摘要 目的探讨丁螺环酮治疗氯丙嗪引起的男性性功能障碍的疗效。方法将本院120例氯丙嗪引起男性性功能障碍者按治疗方案不同分为对照组和观察组,每组60例,治疗12周,对照组患者单用氯丙嗪维持治疗精神分裂症,观察组给予丁螺环酮合并氯丙嗪维持治疗精神分裂症,各组治疗前后采用亚利桑那州性经验量表(ASEX-5)评分,观察两组疗效。结果治疗12周后对照组患者性功能障碍的发生率[66.7%(40/60)]高于观察组[26.7%(16/60),P〈0.01]。观察组治疗前后ASEX-5评分的总分及各因子得分比较差异均有统计学意义(t≥11.12,P〈0.01),治疗12周后观察组患者ASEX-5评分的总分及各因子分与对照组ASEX-5评分的总分及各因子得分差异有统计学意义(t≥7.09,P〈0.01)。结论治疗精神分裂症患者时合用丁螺环酮可降低性功能障碍的发生率,部分患者性功能障碍不能完全治愈。
作者 李业光
出处 《中国医师杂志》 CAS 2011年第10期1429-1431,共3页 Journal of Chinese Physician
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参考文献7

  • 1Olfson M, Uttaro T, Garson WH, et al. Male sexual dysfunction and quality of life in schizophrenia. J Clin Psychiatry, 2005,66 ( 3 ) : 331-338.
  • 2Andreasen NC, Carpenter WT, Kane JM, et al. Remision in schizo phrenia proposed criteria for consensus. Am J Psychiatry, 2005 162(3) :441-449.
  • 3汪向东.阴性与阳性症状量表.心理卫生评定量表手册(增订版),1999:267-276.
  • 4McGahuey GA, Gelenberg AJ, Laukes CA, et al. The Arezona Sexu- al Experience Scale(ASEX) :reliability and validity. J Sex Marital Ther,2000,26( 1 ) :25-40.
  • 5Kelly DL, Conley RR. A randomized double-blind 12-week study of quetiapine, fisperidone or fluphenazine on sexual functioning in people with schizophrenia. ,2006, 31( 3 ) :340-346.
  • 6朱荣鑫,侯钢.抗精神病药对男性精神分裂症患者性功能与催乳素的影响[J].临床精神医学杂志,2010,20(5):322-324. 被引量:8
  • 7李一云,屠监源.丁螺环酮在42例抗抑郁药所致性功能障碍病人中的运用[J].中国新药与临床杂志,2004,23(11):813-815. 被引量:9

二级参考文献10

  • 1Olfson M, Uttaro, Carson WH, et al. Male sexual dysfunction and quality of life in schizophrenia [ J ]. J Clin Psychiatry, 2005,66 : 331-338.
  • 2Andreasen NC, Carpenter WT, Kane JM, et al. Remission in schizophrenia:proposed criteria and rationale for consensus [ J ]. Am J Psychiatry ,2005,162:441-449.
  • 3McGahuey CA, Gelenberg AJ, Laukes CA, et al. The Arizona Sexual Experience Scale ( ASEX ) : reliability and validity [ J ]. J Sex Marital Ther,2000 ,26 :25-40.
  • 4Kelly D. L. Conley RR. A randomized double-blind 12-week study of quetiapine, risperidone or fluphenazine on sexual functioning in people with schizophrenia [ J ] 31:340-346. ,2006,.
  • 5Nicolosi A, Glasser D B, Kim S C, et al. Sexual behaviour and dysfunction and help-seeking patterns in adults aged 40 -80 years in the urban population of Asian countries [ J ]. BJU Int, 2005,95 : 609-614.
  • 6Knegtering H, van MA, Castelein S, et al. What are the effects of antlpsychotlcs on sexual dysfunctions and endocrine functioning [ J ]. Psychoneuroendocrinology,2003,28 ( Suppl 2) : 109-123.
  • 7Westheide J, Cvetanovska G, Albrecht C, et al, Prolactin, Subjective Well-Being and Sexual Dysfunction:An Open Label Observational Study Comparing Quetiapine with Risperidone [ J ]. J Sex Med ,2008,5:2816-2826.
  • 8Corona G, Mannucci E, Fisher AD, et al. Effect of hyperprolactinemia in male patients consulting for sexual dysfunction [ J ]. J Sex Med ,2007,4 : 1485-1493.
  • 9沈一峰,徐筠,顾牛范.选择性5-羟色胺再摄取抑制药与性功能的关系[J].中国新药与临床杂志,2002,21(1):46-50. 被引量:13
  • 10陈晋东,李乐华,陈晓岗,赵靖平,陈远光.丁螺环酮治疗焦虑性障碍的Ⅲ期临床研究[J].中国新药与临床杂志,2002,21(8):453-456. 被引量:13

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