多发性大动脉炎十年随访观察

Takayasu's arteritis involved left renal artery:ten years of follow-up

1例系统随访十年的多发性大动脉炎患者,病史特点如下:36岁女性,病程11年,以恶性高血压、尿检异常起病,肾功能正常,左肾萎缩,双上肢血压不对称,血红细胞沉降率(ESR)、C反应蛋白(CRP)升高,血管造影证实左锁骨下动脉狭窄、右侧无名动脉、颈内动脉起始部狭窄、肾动脉以下腹主动脉轻度狭窄、右肾动脉起始部狭窄及左肾动脉闭塞,确诊为"多发性大动脉炎",予小剂量泼尼松治疗2月,CRP及ESR降至正常,服雷公藤60mg/d维持至今。随访十年来病情平稳,尿蛋白定量持续阴性,肾功能稳定,血压控制良好。

We report a young female patient presenting as malignant hypertension, blood pressure difference in arms, abnormal urine analysis, high ESR and CRP. After performing angiography, she was diagnosed as Takayasu＇s arteritis, treated with prednisolone 30mg/d for two months and tripterygium wilfordii 60 mg/d for ten years. During the ten-year follow-up, the patient remained remission with normal renal function and good-controlled blood pressure.