罗哌卡因与芬太尼持续硬膜外自控镇痛用于无痛分娩96例

Ropivacaine and fentanyl for patient - controlled epidural analgesia for painless labor in 96 cases

目的探讨罗哌卡因与芬太尼持续硬膜外自控镇痛用于无痛分娩的效果及对母婴状况的影响。方法将要求阴道分娩且无产科禁忌证的初产妇192例分为两组，其中做无痛分娩而无麻醉禁忌证的产妇96例，用0．125％罗哌卡因与2μg／ml芬太尼混合液做持续硬膜外自控镇痛（I组）与拒绝分娩镇痛的产妇96例（Ⅱ组）进行比较，观察镇痛效果，胎心情况，不良反应，分娩方式，胎儿宫内窘迫及新生儿窒息情况。结果分娩镇痛效果好，未见明显不良反应，显著降低了剖宫产率，但胎儿宫内窘迫及新生儿窒息情况与Ⅱ组比较差异无统计学意义。结论罗哌卡因与芬太尼持续硬膜外自控镇痛用于无痛分娩镇痛效果确切，母婴健康状况未受影响。

Objective To investigate the efficacy and safety of ropivacaine combined with fentanyl for patient - con- trolled epidural analgesia in painless labor. Methods 192 primigravidae were divided into two groups of 96 each. Group 1 who required painless childbirth without anesthesia contraindications received with 0. 125% ropivacaine combined with fenta- nyl mixed 2 μg/ml dose continuous epidural analgesia liquid. Group 2 received no analgesia and served as control. The vital signs, fetal heart rate adverse reactions, mode of delivery, fetal distress and neonatal asphyxia were recorded. Results The effectiveness of group 1 for analgesia labor was confirmed, the rate of caesarean section of group 1 was much lower than group 2, the rate of anoxia of newborn of 2 groups revealed no significant difference. Conclusion Ropivacaine combined with fenta- nyl is suitable for patient - controlled epidural analgesia in painless labor.