高血压病患者升主动脉弹性功能与冠状动脉狭窄程度的相关性

Relationship of ascending aorta elasticity and severity of coronary artery stenosis in patients with essential hypertension

目的探讨原发性高血压病(EH)患者升主动脉弹性功能与冠状动脉病变狭窄程度的关系。方法对107例EH患者进行冠状动脉造影,分为高血压伴冠心病组(A组,56例)和高血压非冠心病组(B组,51例),应用多普勒组织成像技术测定升主动脉弹性功能,并与Leaman冠状动脉病变评分作相关分析。结果 A组升主动脉扩张性、升主动脉前壁S波的速度均明显低于非冠心病组(P<0.01),且与Leaman冠状动脉病变评分呈负相关。A组升主动脉僵硬度指数明显高于非冠心病组(P<0.01),且与Leaman冠状动脉病变评分呈正相关。结论升主动脉弹性功能可以作为冠状动脉病变严重程度的重要预测因子之一。

Objective To study the relationship of ascending aorta elasticity and severity of coronary artery stenosis in patients with essential hypertension（EH）.Methods On the basis of coronary angiography,107 EH patients were divided into two groups of A[56 cases,EH combined with coronary heart disease（CHD）] and B（51 cases,EH without CHD）.The ascending aorta elasticity was evaluated by Doppler tissue imaging.The relationship between ascending aorta elasticity and Leaman coronary artery score（LCAS） were assessed.Results Aortic distensibility and S velocity of anterior wall of ascending aorta were remarkably lower in group A than those in group B（P〈0.01）,which was negatively correlated to LCAS.Aortic stiffness index was higher in group A than that in group B（P〈0.01）,which was positively correlated to LCAS.Conclusion Ascending aorta elasticity may be taken as one of the indicators for predicting the severity of severity of coronary artery stenosis in patients with EH.