摘要
目的:探讨远志提取物对小鼠脑内多巴胺含量的影响。方法:40只小鼠,随机分为空白对照组,阳性对照组,低剂量组,高剂量组,采用远志提取物进行灌胃,采用荧光分析法测定小鼠脑内多巴胺的含量。结果:远志提取物能够降低小鼠脑内多巴胺的含量,给药组与空白对照组相比有显著差异(P<0.05),与阳性对照组相比无明显差异(P>0.05)。结论:远志提取物可调节小鼠脑内多巴胺的代谢。
Objective： To study the effect of Polygala extract on the brain dopamine level in mice.Methods：Forty mice were randomly divided into four groups,control group,positive control group,low dose group and high dose group.Polygala extract was administered by gastric lavage and the Fluorescence method was used to determine the brain dopamine level in mice.Results： Polygalaceae extract can reduce the dopamine level in the mouse brain,with a significant difference between the treatment group and the control group（P0.01） but with no significant difference compared with the positive control group（P0.05）.Conclusion： Polygala extract can regulate the mouse brain dopamine metabolism.
出处
《黑龙江医药科学》
2011年第5期12-13,共2页
Heilongjiang Medicine and Pharmacy
基金
佳木斯大学科研项目
编号:S2008-22
关键词
远志
小鼠
多巴胺
polygala
mouse
dopamine
